DNA in London

What is DNA?

DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Orchestrating your development from womb to birth, from childhood to adult, from adult to old age; your DNA is your blueprint and your program for life. Nearly every cell in a person's body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA). DNA is maintained in a double helix, spiral-like arrangement and contains 3 essential components: a phosphate molecule, the deoxygenated ribose sugar, and a nitrogenous base. The nitrogenous bases come in four chemical varieties:

adenine (A),
guanine (G),
cytosine (C),
thymine (T).

The precise combination of these, determines our "code". Contained upon the chromosome, these four bases underlie all aspects of physiological function and being. Bases are "read" in sets of threes to give a "codon" e.g. ACTGCTAACGTA, would be read as the four degenerate codons ACT GCT AAC GTA. Each codon corresponds to an amino acid, which is pivotal in the formation of polypeptides and proteins.

Our human DNA consists of about 3 billion bases, and more than 99 percent of those bases are the same in all people. In light of this, how come we are all different?

Single nucleotide polymorphisms (SNPs) account for the slight phenotypic variation that occurs within any population. Referring to a single-base change within any codon of a gene, SNPs commonly incur as a result of a random mutation. Yet apart from the 1% of genetic diversity that is shared between you and your neighbour, or indeed, the 5 % of diversity that"s shared between you and the laboratory mouse, there are potent regulatory elements that make you YOU and unique from anyone else. Contained alongside the DNA, these regulatory elements are analogous to the stops, commas and paragraphs of literary punctuation and mediate whether a gene is expressed, or whether it remains silent.

Interestingly, these elements are highly sensitive to their environment. If a cell in a state of stress, it could cause the elements to interact unfavourably with your DNA, leading to suboptimal physiological function and illness. It is known that under stressed conditions, one becomes more vulnerable to infection, as one"s inflammatory response becomes compromised. Secondary to the regulatory elements, the DNA double helix could also be effected by stress exposure. Fluorescent imaging data has noted the different configurations of water molecules upon exposure to positive and negative intention. It is feasible therefore that DNA could change in a similar way. One may dismiss this as insignificant, yet on the level of the gene, small scale changes have large effects. Namely, gene expression is dependent on how ´open` the helix is and hence, how accessible the genes are to the expression machinery.

In light of the above, the significance of emotions cannot be ignored. Impinging an effect on complex physiology, emotions initiate their influence on the minutest of levels – DNA and genes. Emotions and DNA, like all things in existence, can be reduced to energy. It makes sense that two entities of the same nature (i.e. a collection of charged particles) interact and influence one another. Often we are unnerved by things we cannot see, or things that we cannot empirically validate. For this reason, one may think it strange that the apparant ´immaterial` entity, Emotion, has the capacity to interact with the ´material` DNA. However, one should be assured that the universe does not reduce things to ´material` and ´immaterial`. Stretching beyond that, all in the universe can be reduced to the same – that being resonate, vibrational and creative ENERGY. Upon reflection, one cannot help but be inspired. Inspired with the new realisation that there is more out there then meets the eye, and more to be created then one ever thought possible. The 21st century approach to health embraces this philosophy in bypassing the limitations of conventional medicine. Wellbeing rests not in doctors, presciptions and pills. It rests in you, and you alone.

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